Synthesis of 2-arylbenzimidazole derivatives using nano montmorillonite clay as an efficient catalyst
Authors
Abstract:
Benzimidazoles are among the most important nitrogen-containing heterocyclic compounds that have many pharmaceutical applications, including antitumor, anticancer, anticorrosive, antibacterial, irritant and enzymatic interceptors. In this research, the synthesis of benzimidazoles by using o-phenylenediamine and aldehyde derivatives in the presence of the nano montemurillonite in solvent-free and room temperature conditions has been investigated. All products with relatively good yields were identified by spectroscopic and melting point methods.
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Journal title
volume 7 issue Issue 5, pp. 472-585.
pages 549- 555
publication date 2019-09-01
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